What is the purpose of instrument purification?

In the case of GC-MSMS being quasi-deterministic and quantifiable, can it be purified or not to reduce interference or to protect the instrument?

If it is not purified, it is achieved by sacrificing the instrument. In this way, the maintenance of the instrument must be strengthened. The impurities will be extracted on the column and the detector may be affected. The main reason is that the system becomes dirty and the interference will affect the sensitivity of the instrument.

If it is to protect the instrument or reduce the interference in the test, purification is very important for the column or detector.